Ocular blood flow measurements in healthy human myopic eyes

Background To evaluate the haemodynamic features of young healthy myopes and emmetropes, in order to ascertain the perfusion profile of human myopia and its relationship with axial length prior to reaching a degenerative state. Methods The retrobulbar, microretinal and pulsatile ocular blood flow (POBF) of one eye of each of twenty-two high myopes ( N = 22, mean spherical equivalent (MSE) ≤−5.00D), low myopes ( N = 22, MSE−1.00 to−4.50D) and emmetropes ( N = 22, MSE ± 0.50D) was analyzed using color Doppler Imaging, Heidelberg retinal flowmetry and ocular blood flow analyser (OBF) respectively. Intraocular pressure, axial length (AL), systemic blood pressure, and body mass index were measured. Results When compared to the emmetropes and low myopes, the AL was greater in high myopia ( p