Elevated levels of CA 19-9 and CEA in pancreatic cancer-associated diabetes

Background The relationship between diabetes and pancreatic cancer has been established by more than several decades of research. However, serum levels of CEA and CA 19-9 in diabetic pancreatic cancer has not been shown. Methods Preoperative serum levels of CEA and CA 19-9 and clinicopathological ch...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2010-11, Vol.136 (11), p.1627-1631
Hauptverfasser:	Guo, Qingqu, Kang, Muxing, Zhang, Bo, Chen, Ying, Dong, Xin, Wu, Yulian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - blood Aged Alanine Transaminase - blood Antineoplastic agents Bilirubin - blood Biological and medical sciences Blood Glucose - metabolism CA-19-9 Antigen - blood CA19-9 Cancer Research Carcinoembryonic Antigen - blood CEA Diabetes Diabetes Mellitus - blood Diabetes Mellitus - etiology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Gastroenterology. Liver. Pancreas. Abdomen Hematology Hemoglobins - metabolism Humans Internal Medicine Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Medicine Medicine & Public Health Middle Aged Oncology Original Paper Pancreatic cancer Pancreatic Neoplasms - blood Pancreatic Neoplasms - complications Pharmacology. Drug treatments Reference Values Retrospective Studies Tumors
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Zusammenfassung:	Background The relationship between diabetes and pancreatic cancer has been established by more than several decades of research. However, serum levels of CEA and CA 19-9 in diabetic pancreatic cancer has not been shown. Methods Preoperative serum levels of CEA and CA 19-9 and clinicopathological characteristics were retrospectively analyzed in 79 with or 229 without diabetes in pancreatic ductal adenocarcinoma (PDA) patients. Results Of the 308 PDA patients enrolled, 79 (25.6%) patients had diabetes. The percentage of new-onset diabetes (i.e.
ISSN:	0171-5216 1432-1335
DOI:	10.1007/s00432-010-0820-0