Infection and immune response in the elderly

Infection and immune response in the elderly

A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in...

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Veröffentlicht in:Annals of epidemiology 1992-11, Vol.2 (6), p.813-822
Hauptverfasser: Smith, Philip W., Roccaforte, Jane S., Daly, Pamela B.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Antibody Formation
Cross Infection - immunology
Elderly
Humans
immunity
Immunity, Cellular
immunosenescence
infection
Infection - immunology
Infection Control
Nursing Homes
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Beschreibung
Zusammenfassung:A number of immunologic functions have been shown to decline in an age-related fashion, particularly cell-mediated immunity and antibody response to an immunogen. Underlying degenerative diseases and medications further contribute to the immunologic abnormalities noted in the elderly. The elderly in hospitals and nursing homes are a particularly vulnerable subset, with a high incidence of institutionally acquired infection. Aspects of disease prevention in the elderly are discussed.
ISSN:1047-2797
1873-2585
DOI:10.1016/1047-2797(92)90075-2