Lectins of distinct specificity in Rhodnius prolixus interact selectively with Trypanosoma cruzi

Lectins of different activities were found in the crop, midgut, and hemolymph of the insect Rhodnius prolixus. These were most specific for N-acetyl-D-mannosamine, α-N-acetyl-D-galactosamine, and α- and β-D-galactose, respectively. Lectin receptors were detectable in epimastigote but not in trypomas...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1981-02, Vol.211 (4482), p.597-600
Hauptverfasser: Pereira, M.E.A, Andrade, A.F.B, Ribeiro, J.M.C
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Sprache:eng
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Zusammenfassung:Lectins of different activities were found in the crop, midgut, and hemolymph of the insect Rhodnius prolixus. These were most specific for N-acetyl-D-mannosamine, α-N-acetyl-D-galactosamine, and α- and β-D-galactose, respectively. Lectin receptors were detectable in epimastigote but not in trypomastigote forms of Trypanosoma cruzi, a protozoan parasite of the insect and of humans.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.7006082