Molecular and genetic regulation of osteogenic differentiation of mesenchymal stromal cells

Molecular and genetic regulation of osteogenic differentiation of mesenchymal stromal cells

The review summarizes current concepts concerning the molecular genetic mechanisms of the osteogenic differentiation of mesenchymal stromal cells, which is controlled by a complex of signaling proteins and transcription factors. The interaction of regulatory factors involved in the most important si...

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Veröffentlicht in:Biology bulletin of the Russian Academy of Sciences 2008-06, Vol.35 (3), p.223-232
Hauptverfasser: Kozhevnikova, M. N., Mikaelyan, A. S., Starostin, V. I.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Cell Biology
Differentiation
Ecology
Life Sciences
Mesenchyme
Reviews
Signal transduction
stromal cells
Transcription factors
Zoology
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Beschreibung
Zusammenfassung:The review summarizes current concepts concerning the molecular genetic mechanisms of the osteogenic differentiation of mesenchymal stromal cells, which is controlled by a complex of signaling proteins and transcription factors. The interaction of regulatory factors involved in the most important signaling pathways at different stages of this differentiation is discussed.
ISSN:1062-3590
1608-3059
DOI:10.1134/S1062359008030011