Clinical findings and immunochemical studies in a patient with cryoglobulinaemia

Clinical findings and immunochemical studies in a patient with cryoglobulinaemia

Purpura, shallow ulcers, and livedo were noted in a patient with IgG3-kappa cryoglobulinaemia. The IgG3 cryoglobulin reacted with all IgG subclasses. No complement activation could be demonstrated in fresh normal serum, almost complete conversion of C3, but not of factor B occurred.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Archives of Dermatological Research 1980-08, Vol.268 (3), p.289-296
Hauptverfasser: Kövary, P M, Suter, L, Steinkuhl, H, Schmahl, K
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Complement Activation
Complement System Proteins - analysis
Cryoglobulins - isolation & purification
Humans
Immunoglobulin G - isolation & purification
Immunoglobulin kappa-Chains - isolation & purification
Immunoglobulin Light Chains - isolation & purification
Male
Paraproteinemias - immunology
Paraproteinemias - pathology
Skin - pathology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Purpura, shallow ulcers, and livedo were noted in a patient with IgG3-kappa cryoglobulinaemia. The IgG3 cryoglobulin reacted with all IgG subclasses. No complement activation could be demonstrated in fresh normal serum, almost complete conversion of C3, but not of factor B occurred.
ISSN:0340-3696
1432-069X
DOI:10.1007/BF00404291