ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates

ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates

The biocatalytic potential of Bipolaris sorokiniana was investigated in its ability to modify the monoterpene geraniol and the sesquiterpene alpha-bisabolol as exogenous substrates, using phosphate buffer as reaction medium. The cultures showed a promising oxidative profile, with conversion of geran...

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Veröffentlicht in:Applied microbiology and biotechnology 2003-06, Vol.61 (5/6), p.552-555
Hauptverfasser: Limberger, R.P, Ferreira, L, Castilhos, T, Aleixo, A.M, Petersen, R.Z, Germani, J.C, Zuanazzi, J.A, Fett-Neto, A.G, Henriques, A.T
Format: Artikel
Sprache:eng
Schlagworte:
alpha-bisabolol
Ascomycota - metabolism
Bioengineering
Biological and medical sciences
Bioreactors
Biotechnology
Biotransformation
Bipolaris sorokiniana
Catalysts
Chromatography
Culture Media
Experiments
Fundamental and applied biological sciences. Psychology
Fungi
geraniol
Metabolism
Metabolites
Natural products
Pharmaceutical industry
phosphates
Sesquiterpenes - chemistry
Sesquiterpenes - metabolism
Studies
Terpenes - chemistry
Terpenes - metabolism
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Zusammenfassung:The biocatalytic potential of Bipolaris sorokiniana was investigated in its ability to modify the monoterpene geraniol and the sesquiterpene alpha-bisabolol as exogenous substrates, using phosphate buffer as reaction medium. The cultures showed a promising oxidative profile, with conversion of geraniol to 6-methyl-5-hepten-2-one (74.9% yield) in a 5-day incubation and alpha-bisabolol to bisabolol oxide B (84.2% yield), in a 7-day incubation.
ISSN:0175-7598
1432-0614
DOI:10.1007/s00253-003-1270-2