Antibody persistence six years after two doses of combined hepatitis A and B vaccine

Abstract Persistent immunity to hepatitis A and hepatitis B antibodies six years after vaccination of adolescents (aged 12–15 years) with a combined hepatitis A and B (HAB) vaccine following a 0, 6 month or a 0, 12 month schedule was assessed. Yearly (Year-2–6) serum samples were tested for anti-HAV...

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Veröffentlicht in:	Vaccine 2010-03, Vol.28 (10), p.2222-2226
Hauptverfasser:	Burgess, Margaret A, McIntyre, Peter B, Hellard, Margaret, Ruff, Tilman A, Lefevre, Inge, Bock, Hans L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Age Allergy and Immunology Antibodies Antibody persistence Applied microbiology Biological and medical sciences Child Combined hepatitis A and hepatitis B vaccine Combined vaccines Female Fundamental and applied biological sciences. Psychology Hepatitis Hepatitis A Hepatitis A Antibodies - blood Hepatitis A Vaccines - immunology Hepatitis B Hepatitis B Antibodies - blood Hepatitis B Vaccines - immunology Hepatitis B virus Human viral diseases Humans Immunity Immunization Immunization, Secondary - methods Infectious diseases Liver cirrhosis Long-term protection Male Medical sciences Microbiology Schedules Standard deviation Studies Teenagers Time Factors Vaccination Vaccination - methods Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Combined - immunology Viral diseases Viral hepatitis Young Adult
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Zusammenfassung:	Abstract Persistent immunity to hepatitis A and hepatitis B antibodies six years after vaccination of adolescents (aged 12–15 years) with a combined hepatitis A and B (HAB) vaccine following a 0, 6 month or a 0, 12 month schedule was assessed. Yearly (Year-2–6) serum samples were tested for anti-HAV and anti-HBs using EIA. Subjects with anti-HBs concentrations
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2009.12.053