Comparison of oxidative capacity among leg muscles in humans using gated 31P 2-D chemical shift imaging

In many small animals there are distinct differences in fiber‐type composition among limb muscles, and these differences typically correspond to marked disparities in the oxidative capacities. However, whether there are similar differences in the oxidative capacity among leg muscles in humans is les...

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Veröffentlicht in:NMR in biomedicine 2009-12, Vol.22 (10), p.1063-1071
Hauptverfasser: Forbes, Sean C., Slade, Jill M., Francis, Ryan M., Meyer, Ronald A.
Format: Artikel
Sprache:eng
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Zusammenfassung:In many small animals there are distinct differences in fiber‐type composition among limb muscles, and these differences typically correspond to marked disparities in the oxidative capacities. However, whether there are similar differences in the oxidative capacity among leg muscles in humans is less clear. The purpose of this study was to compare the rate of phosphocreatine (PCr) recovery, a functional in vivo marker of oxidative capacity, in the lateral and medial gastrocnemius, soleus, and the anterior compartment of the leg (primarily the tibialis anterior) of humans. Subjects performed plantar flexion and dorsiflexion gated exercise protocols consisting of 70 sets of three rapid dynamic contractions (
ISSN:0952-3480
1099-1492
DOI:10.1002/nbm.1413