1H-MRSI pattern perturbation in a mouse glioma: the effects of acute hyperglycemia and moderate hypothermia

MR spectroscopic Imaging (MRSI), with PRESS localization, is used here to monitor the effects of acute hyperglycemia in the spectral pattern of 11 mice bearing GL261 gliomas at normothermia (36.5–37.5°C) and at hypothermia (28.5–29.5°C). These in vivo studies were complemented by ex vivo high resolu...

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Veröffentlicht in:	NMR in biomedicine 2010-01, Vol.23 (1), p.23-33
Hauptverfasser:	Simões, R.V., Delgado-Goñi, T., Lope-Piedrafita, S., Arús, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute hyperglycemia Animals Blood Glucose - metabolism Body Temperature brain tumor Disease Models, Animal Female GL261 cells Glioma - metabolism Glioma - pathology Glioma - physiopathology Humans Hyperglycemia - metabolism Hypothermia - metabolism Magnetic Resonance Spectroscopy - methods Mice Mice, Inbred C57BL moderate hypothermia MRS pattern
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