Finegoldia magna: A Forgotten Pathogen in Prosthetic Joint Infection Rediscovered by Molecular Biology

In this study, we describe 13 patients with prosthetic infections due to Finegoldia magna (2% of our tested series). Patients presented with either polymicrobial infection after an open fracture or nosocomial infection after recent prosthesis implantation. Molecular techniques are critical for diagn...

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Veröffentlicht in:	Clinical infectious diseases 2009-10, Vol.49 (8), p.1244-1247
Hauptverfasser:	Levy, Pierre-Yves, Fenollar, Florence, Stein, Andreas, Borrione, Frédéric, Raoult, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Arthritis Biological and medical sciences Bones BRIEF REPORT Diseases of the osteoarticular system DNA, Bacterial - chemistry DNA, Bacterial - genetics DNA, Ribosomal - chemistry DNA, Ribosomal - genetics Female Gram-Positive Bacteria - classification Gram-Positive Bacteria - genetics Gram-Positive Bacteria - isolation & purification Gram-Positive Bacterial Infections - diagnosis Gram-Positive Bacterial Infections - microbiology Humans Infections Infectious diseases Joint prostheses Joint Prosthesis - microbiology Joints Male Medical diagnosis Medical sciences Middle Aged Miscellaneous. Osteoarticular involvement in other diseases Molecular biology Pathogens Peptostreptococcus Polymerase chain reaction Prosthesis-Related Infections - microbiology Prosthetics RNA, Ribosomal, 16S - genetics Rotator cuff Sequence Analysis, DNA Streptococcus infections Studies Transplants & implants Young Adult
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Zusammenfassung:	In this study, we describe 13 patients with prosthetic infections due to Finegoldia magna (2% of our tested series). Patients presented with either polymicrobial infection after an open fracture or nosocomial infection after recent prosthesis implantation. Molecular techniques are critical for diagnosis, and recommended antibiotic prophylaxis has poor activity against F. magna.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/605672