Ganomycins A and B, New Antimicrobial Farnesyl Hydroquinones from the Basidiomycete Ganoderma pfeifferi

Two new farnesyl hydroquinones named ganomycin A (1) and ganomycin B (2) were isolated from Ganoderma pfeifferi, and their structures were elucidated by spectroscopic methods. Both carboxylic acids exhibit antimicrobial activity against several Gram-positive and Gram-negative bacteria.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2000-03, Vol.63 (3), p.416-418
Hauptverfasser:	Mothana, Ramzi A. A, Jansen, Rolf, Jülich, Wolf-Dieter, Lindequist, Ulrike
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Anti-Infective Agents - chemistry Anti-Infective Agents - isolation & purification Anti-Infective Agents - pharmacology antibacterial properties Basidiomycetes Basidiomycota - chemistry Biological and medical sciences chemical constituents of plants chemical structure Ganoderma General pharmacology Gram-negative bacteria Gram-positive bacteria Gram-Positive Bacteria - drug effects hydroquinone Hydroquinones - chemistry Hydroquinones - isolation & purification Hydroquinones - pharmacology Medical sciences Microbial Sensitivity Tests Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments spectral analysis Spectrum Analysis
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Beschreibung
Zusammenfassung:	Two new farnesyl hydroquinones named ganomycin A (1) and ganomycin B (2) were isolated from Ganoderma pfeifferi, and their structures were elucidated by spectroscopic methods. Both carboxylic acids exhibit antimicrobial activity against several Gram-positive and Gram-negative bacteria.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np990381y