Antifungal agents for onychomycoses

Nail fungal infections are considered one of the major dermatological problems due to their high rate of therapeutic failure, management and treatment difficulties. Long-term treatments, inadequate therapies, mycological misdiagnosis and follow-up, secondary alterations of the nail, and resistant mi...

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Veröffentlicht in:Revista iberoamericana de micología 2010-06, Vol.27 (2), p.49-56
Hauptverfasser: Carrillo-Munoz, A J, Tur-Tur, C, Hernandez-Molina, J M, Santos, P, Cardenes, D, Giusiano, G
Format: Artikel
Sprache:spa
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Zusammenfassung:Nail fungal infections are considered one of the major dermatological problems due to their high rate of therapeutic failure, management and treatment difficulties. Long-term treatments, inadequate therapies, mycological misdiagnosis and follow-up, secondary alterations of the nail, and resistant microorganisms, are some of the causes of these complications. Although the discovery of new antifungal agents has provided some effective molecules, none of the current available drugs are totally effective. It is important to continue researching in this field to provide new antifungal agents and combined therapies.Original Abstract: Las infecciones fungicas en las unas se consideran como uno de los mayores problemas en dermatologia. Entre las principales causas estan la alta tasa de fracaso terapeutico, las dificultades en el tratamiento y los largos periodos necesarios, los deficientes diagnosticos y seguimiento micologicos, y las alteraciones secundarias de las unas. Sin embargo, la aparicion de nuevos antifungicos, las nuevas formulaciones, los tratamientos combinados o los nuevos metodos han supuesto mejoras evidentes. No obstante, es imprescindible continuar la investigacion en este campo.
ISSN:1130-1406
DOI:10.1016/j.riam.2010.01.007