STUDIES IN HISTOCHEMISTRY: XXVIII. THE QUANTITATIVE HISTOLOGICAL DISTRIBUTION OF ASCORBIC ACID IN THE ADRENAL GLAND OF THE RAT AND MONKEY

The quantitative histological distribution of ascorbic acid in the adrenal gland of the normal M. rhesus and M. cynomolgus monkey and the albino rat was studied. Although the concentration of ascorbic acid is 4-5 times greater in the gland of the rat than it is in that of the monkey, the same qualitative distribution of ascorbic acid was found in both. The highest concentrations of ascorbic acid were demonstrated in the outer fascicular and in the reticular zones. Only very small concentrations of dehydroascorbic and diketogulonic acids were found in any of the histological regions in the adrenal of the rat.