Induced renal hyperchloraemic acidosis

Induced renal hyperchloraemic acidosis

An infant without previous renal disease was given a carbonic anhydrase inhibitor (No. 6063). Following administration of the drug the serum alkali reserve fell, serum chloride rose and the urine became less acid. The "total carbon dioxide" excreted in the urine was also increased followin...

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Veröffentlicht in:Pediatrics (Evanston) 1954-01, Vol.13 (1), p.64-65
Hauptverfasser: ISRAELS, S, DELORY, G E, GOURLEY, B
Format: Artikel
Sprache:eng
Schlagworte:
Acidosis
Child
Diuretics
Humans
Infant
Kidney Diseases
Old Medline
Sulfanilamides
Sulfonamides - pharmacology
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Zusammenfassung:An infant without previous renal disease was given a carbonic anhydrase inhibitor (No. 6063). Following administration of the drug the serum alkali reserve fell, serum chloride rose and the urine became less acid. The "total carbon dioxide" excreted in the urine was also increased following administration of the inhibitor.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.13.1.64