Comparison of acidic and enzymatic hydrolysis procedures for identification of natural estrogens in pharmaceutical preparations

The usefulness of a distinct enzyme-hydrolyzed preparation for the identification of conjugated and esterified estrogens USP was studied. No significant differences were found when the GLC identification test was performed on the acid-hydrolyzed assay preparation.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1980-12, Vol.69 (12), p.1453-1454
Hauptverfasser:	Carignan, G., Lodge, B.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids comparison of acidic and enzymatic hydrolyses for sample preparation comparison of acidic and enzymatic hydrolysis procedures for sample preparation comparison with acidic hydrolysis procedure Enzymatic hydrolysis-procedure for sample preparation for identification of conjugated and esterified estrogens in pharmaceutical preparations Enzymatic hydrolysis—procedure for sample preparation for identification of conjugated and esterified estrogens in pharmaceutical preparations, comparison with acidic hydrolysis procedure Enzymes Estrogens - analysis Estrogens-identification of conjugated and esterified estrogens in pharmaceutical preparations Estrogens—identification of conjugated and esterified estrogens in pharmaceutical preparations, comparison of acidic and enzymatic hydrolysis procedures for sample preparation GLC-identification of conjugated and esterified estrogens in pharmaceutical preparations GLC—identification of conjugated and esterified estrogens in pharmaceutical preparations, comparison of acidic and enzymatic hydrolyses for sample preparation Hydrolysis
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Beschreibung
Zusammenfassung:	The usefulness of a distinct enzyme-hydrolyzed preparation for the identification of conjugated and esterified estrogens USP was studied. No significant differences were found when the GLC identification test was performed on the acid-hydrolyzed assay preparation.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600691232