Occurrence of highly oxygen-substituted androgens in hemofiltrates of uremic patients

The steroid fraction of hemofiltrate contains a large number of unknown steroids, which were separated by a combination of different chromatographic procedures and finally characterized by gas chromatography mass spectrometry. Besides different isomeric 3,16,17‐trihydroxyandrostanes in a rather pola...

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Veröffentlicht in:Biological Mass Spectrometry 1980-07, Vol.7 (7), p.284-287
Hauptverfasser: Ludwig-Köhn, Helga, Sziedat, Astrid, Spiteller, Gerhard, Matthaei, D., Henning, H. V., Scheler, F.
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Sprache:eng
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Zusammenfassung:The steroid fraction of hemofiltrate contains a large number of unknown steroids, which were separated by a combination of different chromatographic procedures and finally characterized by gas chromatography mass spectrometry. Besides different isomeric 3,16,17‐trihydroxyandrostanes in a rather polar fraction a 3,16,17‐trihydroxy‐11‐ketoandrostane was detected, obviously the first naturally occurring representative of 3,11,16,17 ‐oxygen‐tetrasubstituted androstanes.
ISSN:1052-9306
0306-042X
1096-9888
DOI:10.1002/bms.1200070704