Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora

Three new stereoisomers of condensed tannins (1—3), and four known phenolic compounds (4—7) were isolated from the 80% acetone extract of the roots of Rosa multiflora Thunberg. The structures of these compounds were elucidated using 1D/2D NMR, high resolution (HR)-MS, and circular dichroism (CD) spe...

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Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2010/09/01, Vol.58(9), pp.1227-1231
Hauptverfasser: Park, Kwan Hee, Kim, Sung Kyu, Choi, Sun Eun, Kwon, Joo Hee, Oh, Myung Hwan, Lee, Min Won
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Sprache:eng
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Zusammenfassung:Three new stereoisomers of condensed tannins (1—3), and four known phenolic compounds (4—7) were isolated from the 80% acetone extract of the roots of Rosa multiflora Thunberg. The structures of these compounds were elucidated using 1D/2D NMR, high resolution (HR)-MS, and circular dichroism (CD) spectra. In order to evaluate their anti-oxidative and anti-inflammatory activities, their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and inhibitory activity on nitric oxide (NO) production were determined.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.58.1227