Enantioselective Formal Alkenylations of Imines Catalyzed by Axially Chiral Dicarboxylic Acid Using Vinylogous Aza-Enamines
In the zone: The use of vinylogous aza‐enamaines (hydrazones) as a source of an alkenyl group has been achieved (see scheme). Unmasking of the aza‐enamine moiety opens up a novel approach for the preparation of chiral allylic amines bearing an electron‐withdrawing alkene moiety functionalized at the...
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Veröffentlicht in: | Angewandte Chemie International Edition 2010-09, Vol.49 (38), p.6844-6847 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | In the zone: The use of vinylogous aza‐enamaines (hydrazones) as a source of an alkenyl group has been achieved (see scheme). Unmasking of the aza‐enamine moiety opens up a novel approach for the preparation of chiral allylic amines bearing an electron‐withdrawing alkene moiety functionalized at the electron‐deficient β position. |
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ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.201003600 |