A fillable micro-hollow sphere lesion detection phantom using superposition

The lesion detection performance of SPECT and PET scanners is most commonly evaluated with a phantom containing hollow spheres in a background chamber at a specified radionuclide contrast ratio. However, there are limitations associated with a miniature version of a hollow sphere phantom for small-a...

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Veröffentlicht in:	Physics in medicine & biology 2010-09, Vol.55 (18), p.5363-5381
Hauptverfasser:	DiFilippo, Frank P, Gallo, Sven L, Klatte, Ryan S, Patel, Sagar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Image Processing, Computer-Assisted - instrumentation Phantoms, Imaging Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed
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Zusammenfassung:	The lesion detection performance of SPECT and PET scanners is most commonly evaluated with a phantom containing hollow spheres in a background chamber at a specified radionuclide contrast ratio. However, there are limitations associated with a miniature version of a hollow sphere phantom for small-animal SPECT and PET scanners. One issue is that the 'wall effect' associated with zero activity in the sphere wall and fill port causes significant errors for small diameter spheres. Another issue is that there are practical difficulties in fabricating and in filling very small spheres (
ISSN:	0031-9155 1361-6560
DOI:	10.1088/0031-9155/55/18/007