The Use of Nebulized Trypsin A Preliminary Report

Seventeen patients with respiratory diseases associated with dyspnea and viscous sputum and who were unresponsive to usual therapy were treated with tryptic aerosol. It was shown that tryptic aerosol decreased the viscosity of the sputum. Trypsin, promoting bronchial cleansing, was a helpful adjunct to usual therapy in the majority of these patients. Further evaluation is necessary before the full extent of the clinical usefulness of nebulized trypsin can be established.