IgM globulin response in Q fever (Coxiella Burneti) infections

IgM globulin response in Q fever (Coxiella Burneti) infections

The IgM globulin response has been measured following the onset of primary Q fever infections. A complement fixation test method was used to measure the IgM after separation by ultracentrifugation in a sucrose density gradient. Specific IgM was demonstrable between 2 and 10 wk after onset of symptom...

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Veröffentlicht in:Pathology 1980-01, Vol.12 (3), p.391-396
Hauptverfasser: Murphy, Alan M., Magro, L.
Format: Artikel
Sprache:eng
Schlagworte:
Antibody Formation
Antibody Specificity
Complement Fixation Tests
Coxiella burneti
diagnosis
Humans
IgM globulin
Immunoglobulin M - immunology
Q fever
Q Fever - immunology
Time Factors
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Zusammenfassung:The IgM globulin response has been measured following the onset of primary Q fever infections. A complement fixation test method was used to measure the IgM after separation by ultracentrifugation in a sucrose density gradient. Specific IgM was demonstrable between 2 and 10 wk after onset of symptoms. The test can be used to confirm a recent infection when only a ‘convalescent’ blood specimen has been collected and will be useful in the assessment of workers’ compensation claims.
ISSN:0031-3025
1465-3931
DOI:10.3109/00313028009077101