Effect of phenylhydrazine hydrochloride on Plasmodium lophurae infection in the duck

Effect of phenylhydrazine hydrochloride on Plasmodium lophurae infection in the duck

White Pekin ducks infected with P. lophurae and treated with phenylhydrazine hydrochloride have a lower parasitaemia than untreated ducks. The mechanism by which this effect occurs is discussed. The nuclei of parasitized erythrocytes swell and degenerate following the liberation of the parasites. Th...

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Veröffentlicht in:Transactions of the Royal Society of Tropical Medicine and Hygiene 1953, Vol.47 (1), p.70,IN1,71-70,IN1,76
Hauptverfasser: Rigdon, R.H, Micks, Don W, Breslin, Dorothy
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Ducks
Malaria
Old Medline
Phenylhydrazines - pharmacology
Plasmodium
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Zusammenfassung:White Pekin ducks infected with P. lophurae and treated with phenylhydrazine hydrochloride have a lower parasitaemia than untreated ducks. The mechanism by which this effect occurs is discussed. The nuclei of parasitized erythrocytes swell and degenerate following the liberation of the parasites. These degenerating nuclei are phagocytized. However, some may remain in the circulation and form “smudges” in blood smears.
ISSN:0035-9203
1878-3503
DOI:10.1016/0035-9203(53)90026-1