Amines in Experimental Hypertensions

A sympathomimetic amine, Paredrine, was shown to be a good antihypertensive agent in experimental renal, experimental neurogenic and spontaneous hypertensions in the dog. Other closely related amines failed to possess antihypertensive activity. Paredrine did not prevent the development of experimental renal hypertension. This amine was also without chronic effect on the blood pressure of normotensive dogs.