Antitumor Plants. X. Constituents of Nectandra rigida

The major cytotoxic activity of crude extracts of Nectandra rigida Nees is due to dehydrodiisoeugenol,the sample isolated being slightly enriched in the dextrorotatory enantiomer. Galgravin and two new tetrahydrofuranoid lignans, nectandrin A and nectandrin B, were also isolated and characterized al...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1980-05, Vol.43 (3), p.353-359
Hauptverfasser:	Le Quesne, Philip W, Larrahondo, Jesus F, Raffauf, Robert F
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - isolation & purification Antineoplastic Agents, Phytogenic - isolation & purification Cell Line Humans Nasopharyngeal Neoplasms Neoplasms, Experimental Plant Extracts - pharmacology Plants, Medicinal - analysis
Online-Zugang:	Volltext
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Zusammenfassung:	The major cytotoxic activity of crude extracts of Nectandra rigida Nees is due to dehydrodiisoeugenol,the sample isolated being slightly enriched in the dextrorotatory enantiomer. Galgravin and two new tetrahydrofuranoid lignans, nectandrin A and nectandrin B, were also isolated and characterized along with small quantities of vanillin, 2,6-dimethoxybenzoquinone, and the known lauraceous alkaloid laurelliptine. The neolignans are of potential chemotaxonomic significance in the study of the Lauraceae.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50009a006