3H-imipramine binding in neuronal and glial fractions of horse striatum
The glial fraction prepared from horse striatum contained less than 20% of the specific high affinity 3H-imipramine binding sites found in the neuronal fraction prepared from the same tissue. The binding in the glial fraction was considered to result from minor cross-contamination of the two fractio...
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Veröffentlicht in: | European journal of pharmacology 1980-06, Vol.64 (2), p.191-194 |
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container_title | European journal of pharmacology |
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creator | Briley, Michael S. Fillion, Gilles Beaudoin, Dominique Fillion, Marie-Paule Langer, Salomon Z. |
description | The glial fraction prepared from horse striatum contained less than 20% of the specific high affinity
3H-imipramine binding sites found in the neuronal fraction prepared from the same tissue. The binding in the glial fraction was considered to result from minor cross-contamination of the two fractions. It is thus conclude that there is probably no specific
3H-imipramine binding in glial cells. |
doi_str_mv | 10.1016/0014-2999(80)90046-1 |
format | Article |
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3H-imipramine binding sites found in the neuronal fraction prepared from the same tissue. The binding in the glial fraction was considered to result from minor cross-contamination of the two fractions. It is thus conclude that there is probably no specific
3H-imipramine binding in glial cells.</description><identifier>ISSN: 0014-2999</identifier><identifier>EISSN: 1879-0712</identifier><identifier>DOI: 10.1016/0014-2999(80)90046-1</identifier><identifier>PMID: 7398764</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>3H-Imipramine binding ; Animals ; Antidepressants ; Binding Sites ; Corpus Striatum - metabolism ; Depression ; Glial fraction ; Horses ; Imipramine - metabolism ; In Vitro Techniques ; Neuroglia - metabolism ; Neuronal fraction ; Neurons - metabolism ; Receptors, Serotonin - metabolism ; Tritium</subject><ispartof>European journal of pharmacology, 1980-06, Vol.64 (2), p.191-194</ispartof><rights>1980</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2044-e2a71a93e98d0a167a6086756ca7f4a8392df4eb4aedda97d6111e99a7e5c0e03</citedby><cites>FETCH-LOGICAL-c2044-e2a71a93e98d0a167a6086756ca7f4a8392df4eb4aedda97d6111e99a7e5c0e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0014-2999(80)90046-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7398764$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Briley, Michael S.</creatorcontrib><creatorcontrib>Fillion, Gilles</creatorcontrib><creatorcontrib>Beaudoin, Dominique</creatorcontrib><creatorcontrib>Fillion, Marie-Paule</creatorcontrib><creatorcontrib>Langer, Salomon Z.</creatorcontrib><title>3H-imipramine binding in neuronal and glial fractions of horse striatum</title><title>European journal of pharmacology</title><addtitle>Eur J Pharmacol</addtitle><description>The glial fraction prepared from horse striatum contained less than 20% of the specific high affinity
3H-imipramine binding sites found in the neuronal fraction prepared from the same tissue. The binding in the glial fraction was considered to result from minor cross-contamination of the two fractions. It is thus conclude that there is probably no specific
3H-imipramine binding in glial cells.</description><subject>3H-Imipramine binding</subject><subject>Animals</subject><subject>Antidepressants</subject><subject>Binding Sites</subject><subject>Corpus Striatum - metabolism</subject><subject>Depression</subject><subject>Glial fraction</subject><subject>Horses</subject><subject>Imipramine - metabolism</subject><subject>In Vitro Techniques</subject><subject>Neuroglia - metabolism</subject><subject>Neuronal fraction</subject><subject>Neurons - metabolism</subject><subject>Receptors, Serotonin - metabolism</subject><subject>Tritium</subject><issn>0014-2999</issn><issn>1879-0712</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMo67r6DxR6Ej1UJ23aNBdBFr9gwYuew2wyXSNtuiat4L-36y579DQD78cwD2PnHG448PIWgIs0U0pdVXCtAESZ8gM25ZVUKUieHbLp3nLMTmL8BIBCZcWETWSuKlmKKXvKn1PXunXA1nlKls5b51eJ84mnIXQemwS9TVaNG7c6oOld52PS1clHFyIlsQ8O-6E9ZUc1NpHOdnPG3h8f3ubP6eL16WV-v0hNBkKklKHkqHJSlQXkpcQSqlIWpUFZC6xyldla0FIgWYtK2pJzTkqhpMIAQT5jl9vedei-Boq9bl001DToqRuilgVXhczlaBRbowldjIFqvQ6uxfCjOegNP72BozdwdAX6j5_mY-xi1z8sW7L70A7YqN9tdRqf_HYUdDSOvCHrAple2879f-AXrMx-0g</recordid><startdate>19800613</startdate><enddate>19800613</enddate><creator>Briley, Michael S.</creator><creator>Fillion, Gilles</creator><creator>Beaudoin, Dominique</creator><creator>Fillion, Marie-Paule</creator><creator>Langer, Salomon Z.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19800613</creationdate><title>3H-imipramine binding in neuronal and glial fractions of horse striatum</title><author>Briley, Michael S. ; Fillion, Gilles ; Beaudoin, Dominique ; Fillion, Marie-Paule ; Langer, Salomon Z.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2044-e2a71a93e98d0a167a6086756ca7f4a8392df4eb4aedda97d6111e99a7e5c0e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>3H-Imipramine binding</topic><topic>Animals</topic><topic>Antidepressants</topic><topic>Binding Sites</topic><topic>Corpus Striatum - metabolism</topic><topic>Depression</topic><topic>Glial fraction</topic><topic>Horses</topic><topic>Imipramine - metabolism</topic><topic>In Vitro Techniques</topic><topic>Neuroglia - metabolism</topic><topic>Neuronal fraction</topic><topic>Neurons - metabolism</topic><topic>Receptors, Serotonin - metabolism</topic><topic>Tritium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Briley, Michael S.</creatorcontrib><creatorcontrib>Fillion, Gilles</creatorcontrib><creatorcontrib>Beaudoin, Dominique</creatorcontrib><creatorcontrib>Fillion, Marie-Paule</creatorcontrib><creatorcontrib>Langer, Salomon Z.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Briley, Michael S.</au><au>Fillion, Gilles</au><au>Beaudoin, Dominique</au><au>Fillion, Marie-Paule</au><au>Langer, Salomon Z.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>3H-imipramine binding in neuronal and glial fractions of horse striatum</atitle><jtitle>European journal of pharmacology</jtitle><addtitle>Eur J Pharmacol</addtitle><date>1980-06-13</date><risdate>1980</risdate><volume>64</volume><issue>2</issue><spage>191</spage><epage>194</epage><pages>191-194</pages><issn>0014-2999</issn><eissn>1879-0712</eissn><abstract>The glial fraction prepared from horse striatum contained less than 20% of the specific high affinity
3H-imipramine binding sites found in the neuronal fraction prepared from the same tissue. The binding in the glial fraction was considered to result from minor cross-contamination of the two fractions. It is thus conclude that there is probably no specific
3H-imipramine binding in glial cells.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>7398764</pmid><doi>10.1016/0014-2999(80)90046-1</doi><tpages>4</tpages></addata></record> |
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language | eng |
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source | MEDLINE; Access via ScienceDirect (Elsevier) |
subjects | 3H-Imipramine binding Animals Antidepressants Binding Sites Corpus Striatum - metabolism Depression Glial fraction Horses Imipramine - metabolism In Vitro Techniques Neuroglia - metabolism Neuronal fraction Neurons - metabolism Receptors, Serotonin - metabolism Tritium |
title | 3H-imipramine binding in neuronal and glial fractions of horse striatum |
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