Changed Fc and C3 receptor pattern on human EBV-negative lymphoma cells, following in vitro conversion by EB-virus

Changed Fc and C3 receptor pattern on human EBV-negative lymphoma cells, following in vitro conversion by EB-virus

EBV-conversion of the originally EBV-negative Ramos and BJAB lymphoma lines has led to an increased frequency of C3 receptor positive and a decreased incidence of Fc receptor positive cells in the population. The concentration of C3 receptors per cell has increased as well. This finding supports the...

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Veröffentlicht in:European journal of cancer 1980-04, Vol.16 (4), p.533-538
Hauptverfasser: Jønsson, Viggo, Klein, George, Christensen, Bjarne Egelund
Format: Artikel
Sprache:eng
Schlagworte:
Cell Line
Cell Transformation, Viral
Complement C3
Herpesvirus 4, Human
Lymphoma - immunology
Receptors, Complement - analysis
Receptors, Fc - analysis
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Zusammenfassung:EBV-conversion of the originally EBV-negative Ramos and BJAB lymphoma lines has led to an increased frequency of C3 receptor positive and a decreased incidence of Fc receptor positive cells in the population. The concentration of C3 receptors per cell has increased as well. This finding supports the view that EBV-conversion leads to a modification of surface architecture which, in turn, may explain the changes in nutritional and other biological properties.
ISSN:0014-2964
DOI:10.1016/0014-2964(80)90233-9