Renal excretion of water, sodium and chloride; comparison of the responses of hypertensive patients with those of normal subjects, patients with specific adrenal or pituitary defects, and a normal subject primed with various hormones

There has long been interest in the possibility that a relationship exists between essential hypertension and those endocrine aberrations that involve the hypothalamus, pituitary and adrenal cortex. This paper represents an attempt to study these relationships indirectly by an examination of the manner in which the kidneys of patients with these various diseases handle water, sodium, and chloride.