Effect of calcium on cyclic nucleotide phosphodiesterase in parathyroid tissue

The hydrolysis of cyclic AMP and cyclic GMP by homogenates of normal bovine parathyroid gland and human parathyroid adenomas was decreased by EGTA. When supernatants were chromatographed on DEAE-cellulose it was found that sheep brain calmodulin in the presence of calcium stimulated cyclic AMP and c...

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Veröffentlicht in:	Biochemical and biophysical research communications 1980-06, Vol.94 (3), p.763-768
Hauptverfasser:	Willgoss, D., Jacobi, J.M., de Jersey, J., Bartley, P.C., Lloyd, H.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-AMP Phosphodiesterases - isolation & purification 3',5'-Cyclic-AMP Phosphodiesterases - metabolism 3',5'-Cyclic-GMP Phosphodiesterases - isolation & purification 3',5'-Cyclic-GMP Phosphodiesterases - metabolism Animals Calcium - pharmacology Cattle Egtazic Acid - pharmacology Parathyroid Glands - drug effects Parathyroid Glands - enzymology
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