Amboceptor Titration as a Statistically Controlled Assay
The relative potencies of amboceptors may be determined with data from experiments planned in factorial design and evaluated through the analysis of variance. Dose-response lines are calculated from the percentages of lysis obtained in the presence of a constant amount of complement (1.2 C'H50...
Gespeichert in:
| Veröffentlicht in: | The Journal of immunology (1950) 1952-09, Vol.69 (3), p.241-246 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 246 |
|---|---|
| container_issue | 3 |
| container_start_page | 241 |
| container_title | The Journal of immunology (1950) |
| container_volume | 69 |
| creator | Bier, Otto G Siqueira, Maria Furlanetto, Reynaldo S |
| description | The relative potencies of amboceptors may be determined with data from experiments planned in factorial design and evaluated through the analysis of variance. Dose-response lines are calculated from the percentages of lysis obtained in the presence of a constant amount of complement (1.2 C'H50 units) at three different levels of the unknown and of a standard amboceptor preparation in the range of the supplementary zone.
The method is illustrated with data from a typical assay and the results obtained with two more amboceptors are briefly reported. |
| doi_str_mv | 10.4049/jimmunol.69.3.241 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75141862</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>75141862</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-9e9e5a615ef4736615f27fd2010723bf935448a71a963fb9fc6fc21fcc2e85e83</originalsourceid><addsrcrecordid>eNpFkL1OwzAYRS0EglJ4ABaUBbYU_8WJx6riT6rEQJktx7WpKycutqOob49RC0zf_aRz73AAuEFwRiHlD1vbdUPv3YzxGZlhik7ABFUVLBmD7BRMIMS4RDWrL8BljFsIIYOYnoMLRHJGhE5AM-9ar_Qu-VCsbAoyWd8XMhayeE_5ickq6dy-WPg-Be-cXhfzGOX-CpwZ6aK-Pt4p-Hh6XC1eyuXb8-tiviwVqXEquea6kgxV2tCasBwMrs0aQwRrTFrDSUVpI2skOSOm5UYxozAySmHdVLohU3B_2N0F_zXomERno9LOyV77IYq6QhQ1DGcQHUAVfIxBG7ELtpNhLxAUP7rEry7BuCAi68qd2-P40HZ6_d84-snA3QHY2M_NaIMWscs6Mo7EOI5_Q99Dt3Tf</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75141862</pqid></control><display><type>article</type><title>Amboceptor Titration as a Statistically Controlled Assay</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Bier, Otto G ; Siqueira, Maria ; Furlanetto, Reynaldo S</creator><creatorcontrib>Bier, Otto G ; Siqueira, Maria ; Furlanetto, Reynaldo S</creatorcontrib><description>The relative potencies of amboceptors may be determined with data from experiments planned in factorial design and evaluated through the analysis of variance. Dose-response lines are calculated from the percentages of lysis obtained in the presence of a constant amount of complement (1.2 C'H50 units) at three different levels of the unknown and of a standard amboceptor preparation in the range of the supplementary zone.
The method is illustrated with data from a typical assay and the results obtained with two more amboceptors are briefly reported.</description><identifier>ISSN: 0022-1767</identifier><identifier>EISSN: 1550-6606</identifier><identifier>DOI: 10.4049/jimmunol.69.3.241</identifier><identifier>PMID: 13000134</identifier><language>eng</language><publisher>United States: Am Assoc Immnol</publisher><subject>Biological Assay ; Complement System Proteins ; Humans ; Old Medline</subject><ispartof>The Journal of immunology (1950), 1952-09, Vol.69 (3), p.241-246</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-9e9e5a615ef4736615f27fd2010723bf935448a71a963fb9fc6fc21fcc2e85e83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13000134$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bier, Otto G</creatorcontrib><creatorcontrib>Siqueira, Maria</creatorcontrib><creatorcontrib>Furlanetto, Reynaldo S</creatorcontrib><title>Amboceptor Titration as a Statistically Controlled Assay</title><title>The Journal of immunology (1950)</title><addtitle>J Immunol</addtitle><description>The relative potencies of amboceptors may be determined with data from experiments planned in factorial design and evaluated through the analysis of variance. Dose-response lines are calculated from the percentages of lysis obtained in the presence of a constant amount of complement (1.2 C'H50 units) at three different levels of the unknown and of a standard amboceptor preparation in the range of the supplementary zone.
The method is illustrated with data from a typical assay and the results obtained with two more amboceptors are briefly reported.</description><subject>Biological Assay</subject><subject>Complement System Proteins</subject><subject>Humans</subject><subject>Old Medline</subject><issn>0022-1767</issn><issn>1550-6606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1952</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkL1OwzAYRS0EglJ4ABaUBbYU_8WJx6riT6rEQJktx7WpKycutqOob49RC0zf_aRz73AAuEFwRiHlD1vbdUPv3YzxGZlhik7ABFUVLBmD7BRMIMS4RDWrL8BljFsIIYOYnoMLRHJGhE5AM-9ar_Qu-VCsbAoyWd8XMhayeE_5ickq6dy-WPg-Be-cXhfzGOX-CpwZ6aK-Pt4p-Hh6XC1eyuXb8-tiviwVqXEquea6kgxV2tCasBwMrs0aQwRrTFrDSUVpI2skOSOm5UYxozAySmHdVLohU3B_2N0F_zXomERno9LOyV77IYq6QhQ1DGcQHUAVfIxBG7ELtpNhLxAUP7rEry7BuCAi68qd2-P40HZ6_d84-snA3QHY2M_NaIMWscs6Mo7EOI5_Q99Dt3Tf</recordid><startdate>195209</startdate><enddate>195209</enddate><creator>Bier, Otto G</creator><creator>Siqueira, Maria</creator><creator>Furlanetto, Reynaldo S</creator><general>Am Assoc Immnol</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195209</creationdate><title>Amboceptor Titration as a Statistically Controlled Assay</title><author>Bier, Otto G ; Siqueira, Maria ; Furlanetto, Reynaldo S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-9e9e5a615ef4736615f27fd2010723bf935448a71a963fb9fc6fc21fcc2e85e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1952</creationdate><topic>Biological Assay</topic><topic>Complement System Proteins</topic><topic>Humans</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bier, Otto G</creatorcontrib><creatorcontrib>Siqueira, Maria</creatorcontrib><creatorcontrib>Furlanetto, Reynaldo S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of immunology (1950)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bier, Otto G</au><au>Siqueira, Maria</au><au>Furlanetto, Reynaldo S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amboceptor Titration as a Statistically Controlled Assay</atitle><jtitle>The Journal of immunology (1950)</jtitle><addtitle>J Immunol</addtitle><date>1952-09</date><risdate>1952</risdate><volume>69</volume><issue>3</issue><spage>241</spage><epage>246</epage><pages>241-246</pages><issn>0022-1767</issn><eissn>1550-6606</eissn><abstract>The relative potencies of amboceptors may be determined with data from experiments planned in factorial design and evaluated through the analysis of variance. Dose-response lines are calculated from the percentages of lysis obtained in the presence of a constant amount of complement (1.2 C'H50 units) at three different levels of the unknown and of a standard amboceptor preparation in the range of the supplementary zone.
The method is illustrated with data from a typical assay and the results obtained with two more amboceptors are briefly reported.</abstract><cop>United States</cop><pub>Am Assoc Immnol</pub><pmid>13000134</pmid><doi>10.4049/jimmunol.69.3.241</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1767 |
| ispartof | The Journal of immunology (1950), 1952-09, Vol.69 (3), p.241-246 |
| issn | 0022-1767 1550-6606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75141862 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Biological Assay Complement System Proteins Humans Old Medline |
| title | Amboceptor Titration as a Statistically Controlled Assay |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T04%3A35%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Amboceptor%20Titration%20as%20a%20Statistically%20Controlled%20Assay&rft.jtitle=The%20Journal%20of%20immunology%20(1950)&rft.au=Bier,%20Otto%20G&rft.date=1952-09&rft.volume=69&rft.issue=3&rft.spage=241&rft.epage=246&rft.pages=241-246&rft.issn=0022-1767&rft.eissn=1550-6606&rft_id=info:doi/10.4049/jimmunol.69.3.241&rft_dat=%3Cproquest_cross%3E75141862%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75141862&rft_id=info:pmid/13000134&rfr_iscdi=true |