The relationship of chemical structure to germicidal activity as evidenced by chlorinated phenols

The relationship of chemical structure to germicidal activity as evidenced by chlorinated phenols

The phenol coefficients of 16 of the 19 possible chlorophenols have been determined under controlled conditions of pH. Chlorophenols increase in germicidal activity through the mono-, di-, and trichloro- series but decrease in the tetra- and penta- series when the phenol coefficient is used as a cri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Archives of biochemistry and biophysics 1952-10, Vol.40 (2), p.306-309
Hauptverfasser: Wolf, Paul A., Westveer, W.M.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Infective Agents, Local
Halogenation
Halogens
Hydrocarbons, Halogenated
Old Medline
Phenols
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The phenol coefficients of 16 of the 19 possible chlorophenols have been determined under controlled conditions of pH. Chlorophenols increase in germicidal activity through the mono-, di-, and trichloro- series but decrease in the tetra- and penta- series when the phenol coefficient is used as a criterion of germicidal activity. This irregularity in behavior is discussed and an explanation is offered.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(52)90115-X