Testosterone propionate inhibits maternal aggression in mice

Testosterone propionate inhibits maternal aggression in mice

Daily injections of testosterone propionate (TP) significantly decreased the number of attacks exhibited by lactating female mice toward male intruders. Treatment with TP also depressed the body weights of the dams as well as their lactation performance but these effects were observed long after def...

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Veröffentlicht in:Physiology & behavior 1980-03, Vol.24 (3), p.435-439
1. Verfasser: Svare, Bruce
Format: Artikel
Sprache:eng
Schlagworte:
Aggression - drug effects
Animals
Body Weight - drug effects
Dose-Response Relationship, Drug
Female
Humans
Lactation
Lactation - drug effects
Maternal aggression
Maternal Behavior
Mice
Pregnancy
Testosterone - pharmacology
Testosterone propionate
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Beschreibung
Zusammenfassung:Daily injections of testosterone propionate (TP) significantly decreased the number of attacks exhibited by lactating female mice toward male intruders. Treatment with TP also depressed the body weights of the dams as well as their lactation performance but these effects were observed long after deficits in aggression were noted. The results are discussed in terms of a direct effect of the steroid on central neural tissue mediating the behavior.
ISSN:0031-9384
1873-507X
DOI:10.1016/0031-9384(80)90232-2