Plasma hormones and lipids in men at different risk for coronary heart disease

Plasma estrogen and androgen metabolism in men can be altered by diet as shown in a study of South African black men and North American black and white men. Application of the risk prone Western diet may alter steroid hormone metabolism which alters lipoprotein metabolism and increases the risk of coronary heart disease. Studies of the rate of production and clearance of steroid hormones and lipoproteins under different dietary regimes are necessary to elucidate how diet acts through steroid hormones to alter the rate of lipoprotein synthesis and reduce the risk of coronary heart disease.