Inhibitory effect of Mercurascan on lymphocytes

Inhibitory effect of Mercurascan on lymphocytes

Human lymphocytes treated in vitro with Mercurascan (MSC) have a reduced capacity to form E rosettes and to respond to phytohemagglutinin. MSC was also found to reduce the capacity of mouse lymphocytes to activate the regional lymph nodes of allogeneic recipients and release the lymph node-activatin...

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Veröffentlicht in:Transplantation 1980, Vol.29 (1), p.51-53
Hauptverfasser: Korcáková, L, Kolc, J, Málek, P, Svobodová, J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Female
Fluoresceins - pharmacology
Humans
Hybridization, Genetic
In Vitro Techniques
Lymphocytes - drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Organomercury Compounds - pharmacology
Phytohemagglutinins - pharmacology
Rosette Formation
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Zusammenfassung:Human lymphocytes treated in vitro with Mercurascan (MSC) have a reduced capacity to form E rosettes and to respond to phytohemagglutinin. MSC was also found to reduce the capacity of mouse lymphocytes to activate the regional lymph nodes of allogeneic recipients and release the lymph node-activating factor.
ISSN:0041-1337
DOI:10.1097/00007890-198001000-00011