Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis
Cvc- mutants of Escherichia coli are deficient in the synthesis of cis-vaccenic acid and in the temperature control of fatty acid synthesis. In this communication, it is demonstrated that these mutants lack beta-ketoacyl-acyl carrier protein synthase II. The deficiencies in cis-vaccenate synthesis a...
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Veröffentlicht in: | The Journal of biological chemistry 1980-04, Vol.255 (8), p.3263-3265 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Cvc- mutants of Escherichia coli are deficient in the synthesis of cis-vaccenic acid and in the temperature control of fatty
acid synthesis. In this communication, it is demonstrated that these mutants lack beta-ketoacyl-acyl carrier protein synthase
II. The deficiencies in cis-vaccenate synthesis and synthase II are shown to be due to a lesion in the same gene, fabF. Lesions
in the fabF gene are found to affect growth only when the strain also carries a lesion in the fabB gene, the structural gene
for beta-ketoacyl-acyl carrier protein synthase I. |
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ISSN: | 0021-9258 1083-351X |
DOI: | 10.1016/s0021-9258(19)85692-2 |