Influence of Stimulation of the Nasal Mucous Membrane with Ammonia upon the Adrenaline Secretion from the Suprarenal Gland in Non-anesthetized Dogs

Influence of stimulation of the nasal mucous membrane with am-monia upon the rate of adrenaline secretion was studied on non-anesthetiz-ed dogs, according to the lumber route method of Satake et al. The adrenaline content in the suprarenal vein blood determined by means of the rabbit intestine segment method. In some cases, in which the blood pressure elevated abruptly after the stimulation of the nasal mucous membrane without any material alteration in the heart rate, the adrenaline secretion augmented slightly or remained unaltered. In one case, in which the fluctuation of the blood pressure was not so remarkable, but the heart rate decreased markedly after the stimulation, an enormously augmented adrenaline secretion such as 0.6 γ per kg. per minute from one gland was observed.