The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men
Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of clinical and laboratory investigation 1971-01, Vol.28 (1), p.71-78 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 78 |
|---|---|
| container_issue | 1 |
| container_start_page | 71 |
| container_title | Scandinavian journal of clinical and laboratory investigation |
| container_volume | 28 |
| creator | Lundh, B. Gardner, F. H. |
| description | Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group a marked increase was found for hemopexin. Haptoglobin could be demonstrated in some samples during treatment. In the SIM group hemopexin did not change but haptoglobin increased. On androgens plasma volume decreased in the SCA and increased in the SIM group. |
| doi_str_mv | 10.3109/00365517109090665 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_infor</sourceid><recordid>TN_cdi_proquest_miscellaneous_75016240</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>75016240</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-6525b95cf1136bbbf786a83efcce630203519f1179f4765d2521342bc7edb84e3</originalsourceid><addsrcrecordid>eNp9Uctu1DAUtRBVmRY-gAWSV-wCdhw7iWBTDQUqtaLSDGwjx7kmLo49tR2V-Zt-Kp7OqBJCVF742uehq3MQek3JO0ZJ-54QJjindZ7zEYI_QwvKSVnUohHP0WKHF5nAXqCTGG9IfrOmOkbHVdu2JSMLdL8eAZ9rDSphr_EaYvIxQfAOsHH4epRhkspb_9MoafEnHyFinwEr4yTxD2_nCbB0w-5z5fO8gjBP-Dr4BMbFBxOZDLgU8Z1JI14Z9csCXoK1-MzBZOSDPPNW8HuW1m7xxbTJapfwFbiX6EhLG-HV4T5F3z-fr5dfi8tvXy6WZ5eFqmqaCsFL3rdcaUqZ6Pte142QDQOtFAhGSsI4bTNYt7qqBR9KXlJWlb2qYeibCtgperv33QR_O-cYuslElZeUDvwcu5oTKsqKZCLdE1XwMQbQ3SaYSYZtR0m3a6X7p5WseXMwn_sJhkfFoYaMf9zjxmmfA7_zwQ5dklvrgw7SKRN31v-3__CXfARp06hkgO7Gz8Hl3J5Y7g9a_63X</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75016240</pqid></control><display><type>article</type><title>The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men</title><source>MEDLINE</source><source>Taylor & Francis Medical Library - CRKN</source><source>Taylor & Francis Journals Complete</source><creator>Lundh, B. ; Gardner, F. H.</creator><creatorcontrib>Lundh, B. ; Gardner, F. H.</creatorcontrib><description>Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group a marked increase was found for hemopexin. Haptoglobin could be demonstrated in some samples during treatment. In the SIM group hemopexin did not change but haptoglobin increased. On androgens plasma volume decreased in the SCA and increased in the SIM group.</description><identifier>ISSN: 0036-5513</identifier><identifier>EISSN: 1502-7686</identifier><identifier>DOI: 10.3109/00365517109090665</identifier><identifier>PMID: 4999230</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Alpha ; anemia ; Anemia, Sickle Cell - blood ; antitrypsin ; Blood Protein Electrophoresis ; blood proteins ; Blood Proteins - analysis ; Child ; Erectile Dysfunction - blood ; Female ; haptoglobin ; Haptoglobins - analysis ; hemopexin ; Hemopexin - blood ; Humans ; Immunodiffusion ; Immunoglobulin A - analysis ; Immunoglobulin G - analysis ; immunoglobulins ; Male ; Middle Aged ; Mucoproteins - blood ; orosomucoid ; plasma volume ; Plasma Volume - drug effects ; Plasminogen - analysis ; sickle cell ; Testosterone - pharmacology ; Time Factors ; transferrin ; Transferrin - analysis ; Trypsin Inhibitors - blood</subject><ispartof>Scandinavian journal of clinical and laboratory investigation, 1971-01, Vol.28 (1), p.71-78</ispartof><rights>1971 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-6525b95cf1136bbbf786a83efcce630203519f1179f4765d2521342bc7edb84e3</citedby><cites>FETCH-LOGICAL-c471t-6525b95cf1136bbbf786a83efcce630203519f1179f4765d2521342bc7edb84e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/00365517109090665$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/00365517109090665$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,59647,59753,60436,60542,61221,61256,61402,61437</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4999230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lundh, B.</creatorcontrib><creatorcontrib>Gardner, F. H.</creatorcontrib><title>The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men</title><title>Scandinavian journal of clinical and laboratory investigation</title><addtitle>Scand J Clin Lab Invest</addtitle><description>Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group a marked increase was found for hemopexin. Haptoglobin could be demonstrated in some samples during treatment. In the SIM group hemopexin did not change but haptoglobin increased. On androgens plasma volume decreased in the SCA and increased in the SIM group.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Alpha</subject><subject>anemia</subject><subject>Anemia, Sickle Cell - blood</subject><subject>antitrypsin</subject><subject>Blood Protein Electrophoresis</subject><subject>blood proteins</subject><subject>Blood Proteins - analysis</subject><subject>Child</subject><subject>Erectile Dysfunction - blood</subject><subject>Female</subject><subject>haptoglobin</subject><subject>Haptoglobins - analysis</subject><subject>hemopexin</subject><subject>Hemopexin - blood</subject><subject>Humans</subject><subject>Immunodiffusion</subject><subject>Immunoglobulin A - analysis</subject><subject>Immunoglobulin G - analysis</subject><subject>immunoglobulins</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mucoproteins - blood</subject><subject>orosomucoid</subject><subject>plasma volume</subject><subject>Plasma Volume - drug effects</subject><subject>Plasminogen - analysis</subject><subject>sickle cell</subject><subject>Testosterone - pharmacology</subject><subject>Time Factors</subject><subject>transferrin</subject><subject>Transferrin - analysis</subject><subject>Trypsin Inhibitors - blood</subject><issn>0036-5513</issn><issn>1502-7686</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uctu1DAUtRBVmRY-gAWSV-wCdhw7iWBTDQUqtaLSDGwjx7kmLo49tR2V-Zt-Kp7OqBJCVF742uehq3MQek3JO0ZJ-54QJjindZ7zEYI_QwvKSVnUohHP0WKHF5nAXqCTGG9IfrOmOkbHVdu2JSMLdL8eAZ9rDSphr_EaYvIxQfAOsHH4epRhkspb_9MoafEnHyFinwEr4yTxD2_nCbB0w-5z5fO8gjBP-Dr4BMbFBxOZDLgU8Z1JI14Z9csCXoK1-MzBZOSDPPNW8HuW1m7xxbTJapfwFbiX6EhLG-HV4T5F3z-fr5dfi8tvXy6WZ5eFqmqaCsFL3rdcaUqZ6Pte142QDQOtFAhGSsI4bTNYt7qqBR9KXlJWlb2qYeibCtgperv33QR_O-cYuslElZeUDvwcu5oTKsqKZCLdE1XwMQbQ3SaYSYZtR0m3a6X7p5WseXMwn_sJhkfFoYaMf9zjxmmfA7_zwQ5dklvrgw7SKRN31v-3__CXfARp06hkgO7Gz8Hl3J5Y7g9a_63X</recordid><startdate>19710101</startdate><enddate>19710101</enddate><creator>Lundh, B.</creator><creator>Gardner, F. H.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19710101</creationdate><title>The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men</title><author>Lundh, B. ; Gardner, F. H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-6525b95cf1136bbbf786a83efcce630203519f1179f4765d2521342bc7edb84e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Alpha</topic><topic>anemia</topic><topic>Anemia, Sickle Cell - blood</topic><topic>antitrypsin</topic><topic>Blood Protein Electrophoresis</topic><topic>blood proteins</topic><topic>Blood Proteins - analysis</topic><topic>Child</topic><topic>Erectile Dysfunction - blood</topic><topic>Female</topic><topic>haptoglobin</topic><topic>Haptoglobins - analysis</topic><topic>hemopexin</topic><topic>Hemopexin - blood</topic><topic>Humans</topic><topic>Immunodiffusion</topic><topic>Immunoglobulin A - analysis</topic><topic>Immunoglobulin G - analysis</topic><topic>immunoglobulins</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mucoproteins - blood</topic><topic>orosomucoid</topic><topic>plasma volume</topic><topic>Plasma Volume - drug effects</topic><topic>Plasminogen - analysis</topic><topic>sickle cell</topic><topic>Testosterone - pharmacology</topic><topic>Time Factors</topic><topic>transferrin</topic><topic>Transferrin - analysis</topic><topic>Trypsin Inhibitors - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lundh, B.</creatorcontrib><creatorcontrib>Gardner, F. H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of clinical and laboratory investigation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lundh, B.</au><au>Gardner, F. H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men</atitle><jtitle>Scandinavian journal of clinical and laboratory investigation</jtitle><addtitle>Scand J Clin Lab Invest</addtitle><date>1971-01-01</date><risdate>1971</risdate><volume>28</volume><issue>1</issue><spage>71</spage><epage>78</epage><pages>71-78</pages><issn>0036-5513</issn><eissn>1502-7686</eissn><abstract>Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group a marked increase was found for hemopexin. Haptoglobin could be demonstrated in some samples during treatment. In the SIM group hemopexin did not change but haptoglobin increased. On androgens plasma volume decreased in the SCA and increased in the SIM group.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>4999230</pmid><doi>10.3109/00365517109090665</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5513 |
| ispartof | Scandinavian journal of clinical and laboratory investigation, 1971-01, Vol.28 (1), p.71-78 |
| issn | 0036-5513 1502-7686 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75016240 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adolescent Adult Alpha anemia Anemia, Sickle Cell - blood antitrypsin Blood Protein Electrophoresis blood proteins Blood Proteins - analysis Child Erectile Dysfunction - blood Female haptoglobin Haptoglobins - analysis hemopexin Hemopexin - blood Humans Immunodiffusion Immunoglobulin A - analysis Immunoglobulin G - analysis immunoglobulins Male Middle Aged Mucoproteins - blood orosomucoid plasma volume Plasma Volume - drug effects Plasminogen - analysis sickle cell Testosterone - pharmacology Time Factors transferrin Transferrin - analysis Trypsin Inhibitors - blood |
| title | The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T03%3A02%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_infor&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Effect%20of%20Testosterone%20in%20Pharmacological%20Doses%20on%20Plasma%20Volume%20and%20on%20Some%20Serum%20Proteins%20in%20Patients%20with%20Sickle%20Cell%20Anemia%20and%20in%20Sexually%20Impotent%20Men&rft.jtitle=Scandinavian%20journal%20of%20clinical%20and%20laboratory%20investigation&rft.au=Lundh,%20B.&rft.date=1971-01-01&rft.volume=28&rft.issue=1&rft.spage=71&rft.epage=78&rft.pages=71-78&rft.issn=0036-5513&rft.eissn=1502-7686&rft_id=info:doi/10.3109/00365517109090665&rft_dat=%3Cproquest_infor%3E75016240%3C/proquest_infor%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75016240&rft_id=info:pmid/4999230&rfr_iscdi=true |