The Effect of Testosterone in Pharmacological Doses on Plasma Volume and on Some Serum Proteins in Patients with Sickle Cell Anemia and in Sexually Impotent Men

Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group...

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Veröffentlicht in:	Scandinavian journal of clinical and laboratory investigation 1971-01, Vol.28 (1), p.71-78
Hauptverfasser:	Lundh, B., Gardner, F. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alpha anemia Anemia, Sickle Cell - blood antitrypsin Blood Protein Electrophoresis blood proteins Blood Proteins - analysis Child Erectile Dysfunction - blood Female haptoglobin Haptoglobins - analysis hemopexin Hemopexin - blood Humans Immunodiffusion Immunoglobulin A - analysis Immunoglobulin G - analysis immunoglobulins Male Middle Aged Mucoproteins - blood orosomucoid plasma volume Plasma Volume - drug effects Plasminogen - analysis sickle cell Testosterone - pharmacology Time Factors transferrin Transferrin - analysis Trypsin Inhibitors - blood
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Zusammenfassung:	Serum levels of 13 plasma proteins and the plasma volumes were estimated in 10 patients with sickle cell anemia (SCA) and in 6 sexually impotent males (SIM) before and during treatment with high-dose androgens. In both groups an increase was seen for α1-antitrypsin and orosomucoid. In the SCA group a marked increase was found for hemopexin. Haptoglobin could be demonstrated in some samples during treatment. In the SIM group hemopexin did not change but haptoglobin increased. On androgens plasma volume decreased in the SCA and increased in the SIM group.
ISSN:	0036-5513 1502-7686
DOI:	10.3109/00365517109090665