Effect of Coagulase-Globulin on Residual Prothrombin Activity (Prothrombin Consumption) of Hemophilic Blood

Summary 1. The coagulase-globulin fraction of normal human plasma not only reduces the coagulation time of hemophilic blood but also alters the pattern of residual serum prothrombin activity in the direction of normal. 2. An equivalent amount of normal blood produces the same effect. 3. Simple dilut...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1952-05, Vol.80 (1), p.76-77
Hauptverfasser:	Miale, John B., Wenzel, Frederick J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation Tests Coagulase Globulins Hemophilia A - blood Hemostatics Humans Old Medline Prothrombin von Willebrand Diseases
Online-Zugang:	Volltext
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Zusammenfassung:	Summary 1. The coagulase-globulin fraction of normal human plasma not only reduces the coagulation time of hemophilic blood but also alters the pattern of residual serum prothrombin activity in the direction of normal. 2. An equivalent amount of normal blood produces the same effect. 3. Simple dilution of hemophilic blood with saline by itself produces significant alterations in coagulation time and residual prothrombin.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-80-19528