Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.
Summary (1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significan...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1952-01, Vol.79 (1), p.59-62 |
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| container_end_page | 62 |
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| container_issue | 1 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 79 |
| creator | Rambach, W. A. Moomaw, D. R. Alt, H. L. Cooper, J. A. D. |
| description | Summary
(1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significant decrease in the relative rate of formation of DNA in the bone marrow and spleen during a period of 5 1/2 hours. (3) The significance of these observations is discussed. |
| doi_str_mv | 10.3181/00379727-79-19272 |
| format | Article |
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(1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significant decrease in the relative rate of formation of DNA in the bone marrow and spleen during a period of 5 1/2 hours. (3) The significance of these observations is discussed.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-79-19272</identifier><identifier>PMID: 14892038</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Barbiturates - pharmacology ; Bone Marrow - metabolism ; Nucleic Acids ; Old Medline ; Pentobarbital ; Reference Values ; Sodium ; Spleen - drug effects</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1952-01, Vol.79 (1), p.59-62</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c253t-c41694a1679dc6f3b03dbb11022e60346922c6432fb517694ad12153fc6f5fa23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14892038$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rambach, W. A.</creatorcontrib><creatorcontrib>Moomaw, D. R.</creatorcontrib><creatorcontrib>Alt, H. L.</creatorcontrib><creatorcontrib>Cooper, J. A. D.</creatorcontrib><title>Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
(1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significant decrease in the relative rate of formation of DNA in the bone marrow and spleen during a period of 5 1/2 hours. (3) The significance of these observations is discussed.</description><subject>Barbiturates - pharmacology</subject><subject>Bone Marrow - metabolism</subject><subject>Nucleic Acids</subject><subject>Old Medline</subject><subject>Pentobarbital</subject><subject>Reference Values</subject><subject>Sodium</subject><subject>Spleen - drug effects</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1952</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAURC0EoqXwAWyQV-wSfO0krpcF8ZKgIPHYWo5jV6mcuNiJEH9PQovYsbqLOTO6MwidAkkZzOGCEMYFpzzhIgFBOd1DU8hZnrBCiH00HfVkBCboKMY1IZBzWhyiCWRzQQmbT9Fq2Wtnao0Xuq7wo-lU6V0dG-wtvvStwY8qBP-JVVvhl40zpk3xfYqXPjTK4XflehN_xGtrje5G24uv6r7Bz6btfKlCWXfKpcfowCoXzcnuztDbzfXr1V3y8HR7f7V4SDTNWZfoDAqRKSi4qHRhWUlYVZYAhFJTEJYVglJdZIzaMgc-ohXQobId4NwqymbofJu7Cf5j-K2TTR21cU61xvdR8pyQDGAEYQvq4GMMxspNqBsVviQQOa4rf9eVXMifdQfP2S68LxtT_Tl2cw5AugWiWhm59n1oh7L_JH4DoUuAdg</recordid><startdate>195201</startdate><enddate>195201</enddate><creator>Rambach, W. A.</creator><creator>Moomaw, D. R.</creator><creator>Alt, H. L.</creator><creator>Cooper, J. A. D.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195201</creationdate><title>Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.</title><author>Rambach, W. A. ; Moomaw, D. R. ; Alt, H. L. ; Cooper, J. A. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c253t-c41694a1679dc6f3b03dbb11022e60346922c6432fb517694ad12153fc6f5fa23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1952</creationdate><topic>Barbiturates - pharmacology</topic><topic>Bone Marrow - metabolism</topic><topic>Nucleic Acids</topic><topic>Old Medline</topic><topic>Pentobarbital</topic><topic>Reference Values</topic><topic>Sodium</topic><topic>Spleen - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rambach, W. A.</creatorcontrib><creatorcontrib>Moomaw, D. R.</creatorcontrib><creatorcontrib>Alt, H. L.</creatorcontrib><creatorcontrib>Cooper, J. A. D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rambach, W. A.</au><au>Moomaw, D. R.</au><au>Alt, H. L.</au><au>Cooper, J. A. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1952-01</date><risdate>1952</risdate><volume>79</volume><issue>1</issue><spage>59</spage><epage>62</epage><pages>59-62</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
(1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significant decrease in the relative rate of formation of DNA in the bone marrow and spleen during a period of 5 1/2 hours. (3) The significance of these observations is discussed.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14892038</pmid><doi>10.3181/00379727-79-19272</doi><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1952-01, Vol.79 (1), p.59-62 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Barbiturates - pharmacology Bone Marrow - metabolism Nucleic Acids Old Medline Pentobarbital Reference Values Sodium Spleen - drug effects |
| title | Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital. |
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