Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.

Nucleic Acid Metabolism of Bone Marrow and Spleen. I. Normal Values and Effect of Sodium Pentobarbital.

Summary (1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significan...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1952-01, Vol.79 (1), p.59-62
Hauptverfasser: Rambach, W. A., Moomaw, D. R., Alt, H. L., Cooper, J. A. D.
Format: Artikel
Sprache:eng
Schlagworte:
Barbiturates - pharmacology
Bone Marrow - metabolism
Nucleic Acids
Old Medline
Pentobarbital
Reference Values
Sodium
Spleen - drug effects
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Zusammenfassung:Summary (1) Normal values are presented for the desoxyribose nucleic acid phosphorus and ribose nucleic acid phosphorus as well as the rate of uptake of P32 by the DNA and RNA in the bone marrow and spleen of adult rats. (2) Anesthetic doses of sodium pentobarbital were found to produce a significant decrease in the relative rate of formation of DNA in the bone marrow and spleen during a period of 5 1/2 hours. (3) The significance of these observations is discussed.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-79-19272