Secondary Products of Itanoxone
Itanoxone synthesis by Friedel-Crafts reaction between itaconic anhydride and 2-chlorobiphenyl was studied. Five isomers corresponding to possible impurities were prepared and studied to perfect a reliable and practical method to detect these impurities in itanoxone.
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1980-01, Vol.69 (1), p.49-53 |
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| container_end_page | 53 |
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| container_issue | 1 |
| container_start_page | 49 |
| container_title | Journal of pharmaceutical sciences |
| container_volume | 69 |
| creator | Rieu, Jean-Pierre Mouzin, Gilbert Cousse, Henri Boucherle, Andre |
| description | Itanoxone synthesis by Friedel-Crafts reaction between itaconic anhydride and 2-chlorobiphenyl was studied. Five isomers corresponding to possible impurities were prepared and studied to perfect a reliable and practical method to detect these impurities in itanoxone. |
| doi_str_mv | 10.1002/jps.2600690114 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1980-01, Vol.69 (1), p.49-53 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74989201 |
| source | MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Biphenyl Compounds - chemical synthesis Biphenyl Compounds - isolation & purification Butyrophenones - chemical synthesis Butyrophenones - isolation & purification Chromatography, Thin Layer Hydrogenation Hypolipidemic Agents - chemical synthesis Hypolipidemic Agents - isolation & purification Hypolipidemic agents-itanoxone Hypolipidemic agents—itanoxone, synthesis, synthesis and detection of impurities Hypouricemic agents-itanoxone Hypouricemic agents—itanoxone, synthesis, synthesis and detection of impurities Isomerism Itanoxone-synthesis Itanoxone—synthesis, synthesis and detection of impurities synthesis synthesis and detection of impurities |
| title | Secondary Products of Itanoxone |
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