Further Studies on Relationship Between Human Serum Cholinesterase and Serum Albumin
Conclusion The previously observed (1,2) correlation of serum albumin and serum cholinesterase values is prlobably due to the simultaneous production of these two proteins by related synthesizing mechanisms in the liver. Albumin does not act as a precursor of serum cholinesterase. Changes in the lev...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1952-04, Vol.79 (4), p.686-690 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Levine, Milton Gjelhaug Suran, Anita A. |
description | Conclusion
The previously observed (1,2) correlation of serum albumin and serum cholinesterase values is prlobably due to the simultaneous production of these two proteins by related synthesizing mechanisms in the liver. Albumin does not act as a precursor of serum cholinesterase. Changes in the level of this enzyme reflect the changing ability of the liver to produce both serum cholinesterase and serum albumin. It is suggested that serum cholinesterase determinations are of prognostic value in liver disease and that cholinesterase determinations may be used as an indication of albumin synthesis, particularly in the presence of administered albumin. |
doi_str_mv | 10.3181/00379727-79-19486 |
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The previously observed (1,2) correlation of serum albumin and serum cholinesterase values is prlobably due to the simultaneous production of these two proteins by related synthesizing mechanisms in the liver. Albumin does not act as a precursor of serum cholinesterase. Changes in the level of this enzyme reflect the changing ability of the liver to produce both serum cholinesterase and serum albumin. It is suggested that serum cholinesterase determinations are of prognostic value in liver disease and that cholinesterase determinations may be used as an indication of albumin synthesis, particularly in the presence of administered albumin.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-79-19486</identifier><identifier>PMID: 14920535</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Blood Proteins ; Cholinesterases - blood ; Humans ; Old Medline ; Serum Albumin</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1952-04, Vol.79 (4), p.686-690</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-a287b0e78858157da2c21c8199f86483e4e0382c0d9e90b77051e3660156c8923</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14920535$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Levine, Milton Gjelhaug</creatorcontrib><creatorcontrib>Suran, Anita A.</creatorcontrib><title>Further Studies on Relationship Between Human Serum Cholinesterase and Serum Albumin</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Conclusion
The previously observed (1,2) correlation of serum albumin and serum cholinesterase values is prlobably due to the simultaneous production of these two proteins by related synthesizing mechanisms in the liver. Albumin does not act as a precursor of serum cholinesterase. Changes in the level of this enzyme reflect the changing ability of the liver to produce both serum cholinesterase and serum albumin. It is suggested that serum cholinesterase determinations are of prognostic value in liver disease and that cholinesterase determinations may be used as an indication of albumin synthesis, particularly in the presence of administered albumin.</description><subject>Blood Proteins</subject><subject>Cholinesterases - blood</subject><subject>Humans</subject><subject>Old Medline</subject><subject>Serum Albumin</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1952</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD9PwzAUxC0EoqXwAViQJ7YU_0lieyxVS5EqIdEyW07ySlMlTrFjIb49CQ1iY3rD_e507xC6pWTKqaQPhHChBBORUBFVsUzP0JgmPIl4qtQ5Gvd61AMjdOX9gRCaCJZeohGNFSMdOEbbZXDtHhzetKEowePG4leoTFs21u_LI36E9hPA4lWojcUbcKHG831TlRZ8C854wMYWgzCrslCX9hpd7Ezl4Wa4E_S2XGznq2j98vQ8n62jnHPZRoZJkREQUiaya1YYljOaS6rUTqax5BAD4ZLlpFCgSCYESSjwNO3eSHOpGJ-g-1Pu0TUfoeuj69LnUFXGQhO8FrHqs3uQnsDcNd472OmjK2vjvjQlup9S_06phdI_U3aeuyE8ZDUUf45huw6YngBv3kEfmuBs9-w_id_CznsX</recordid><startdate>195204</startdate><enddate>195204</enddate><creator>Levine, Milton Gjelhaug</creator><creator>Suran, Anita A.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195204</creationdate><title>Further Studies on Relationship Between Human Serum Cholinesterase and Serum Albumin</title><author>Levine, Milton Gjelhaug ; Suran, Anita A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-a287b0e78858157da2c21c8199f86483e4e0382c0d9e90b77051e3660156c8923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1952</creationdate><topic>Blood Proteins</topic><topic>Cholinesterases - blood</topic><topic>Humans</topic><topic>Old Medline</topic><topic>Serum Albumin</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Levine, Milton Gjelhaug</creatorcontrib><creatorcontrib>Suran, Anita A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levine, Milton Gjelhaug</au><au>Suran, Anita A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Further Studies on Relationship Between Human Serum Cholinesterase and Serum Albumin</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1952-04</date><risdate>1952</risdate><volume>79</volume><issue>4</issue><spage>686</spage><epage>690</epage><pages>686-690</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Conclusion
The previously observed (1,2) correlation of serum albumin and serum cholinesterase values is prlobably due to the simultaneous production of these two proteins by related synthesizing mechanisms in the liver. Albumin does not act as a precursor of serum cholinesterase. Changes in the level of this enzyme reflect the changing ability of the liver to produce both serum cholinesterase and serum albumin. It is suggested that serum cholinesterase determinations are of prognostic value in liver disease and that cholinesterase determinations may be used as an indication of albumin synthesis, particularly in the presence of administered albumin.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14920535</pmid><doi>10.3181/00379727-79-19486</doi><tpages>5</tpages></addata></record> |
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subjects | Blood Proteins Cholinesterases - blood Humans Old Medline Serum Albumin |
title | Further Studies on Relationship Between Human Serum Cholinesterase and Serum Albumin |
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