Tooth Induction in Chick Epithelium: Expression of Quiescent Genes for Enamel Synthesis

Tooth Induction in Chick Epithelium: Expression of Quiescent Genes for Enamel Synthesis

Intraocular grafts of chick epithelium combined with mouse molar mesenchyme produced a variety of dental structures including perfectly formed crowns with differentiated ameloblasts depositing enamel matrix. The results suggest that the loss of teeth in Aves did not result from a loss of genetic cod...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1980-02, Vol.207 (4434), p.993-995
Hauptverfasser: Kollar, E. J., Fisher, C.
Format: Artikel
Sprache:eng
Schlagworte:
Amelogenesis
Animal glands
Animals
Biological evolution
Bones
Chick Embryo - cytology
Culture Techniques
Dental Enamel Proteins - biosynthesis
Dental Enamel Proteins - genetics
Embryonic Induction
Epithelial Cells
Epithelium
Evolutionary genetics
Genes
Keratinization
Mandible - cytology
Mesoderm - cytology
Mice
Odontoblasts
Odontogenesis
Papillae
Teeth
Tooth enamel
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Zusammenfassung:Intraocular grafts of chick epithelium combined with mouse molar mesenchyme produced a variety of dental structures including perfectly formed crowns with differentiated ameloblasts depositing enamel matrix. The results suggest that the loss of teeth in Aves did not result from a loss of genetic coding for enamel synthesis in the oral epithelium but from an alteration in the tissue interactions requisite for odontogenesis.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.7352302