Effect of zinc on hyperammonemia in sickle cell anemia subjects
An increase in plasma ammonia level in human volunteers on restricted zinc intake, and in zinc‐deficient rats, has recently been reported. Inasmuch as zinc deficiency has been observed in sickle cell anemia patients, we measured plasma ammonia levels in such subjects. In this report we document hype...
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Veröffentlicht in: | American journal of hematology 1979-01, Vol.7 (4), p.323-327 |
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creator | Prasad, Ananda S. Rabbani, Parviz Warth, James A. |
description | An increase in plasma ammonia level in human volunteers on restricted zinc intake, and in zinc‐deficient rats, has recently been reported. Inasmuch as zinc deficiency has been observed in sickle cell anemia patients, we measured plasma ammonia levels in such subjects. In this report we document hyperammonemia in sickle cell anemia patients that was corrected with zinc therapy. |
doi_str_mv | 10.1002/ajh.2830070404 |
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Inasmuch as zinc deficiency has been observed in sickle cell anemia patients, we measured plasma ammonia levels in such subjects. In this report we document hyperammonemia in sickle cell anemia patients that was corrected with zinc therapy.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.2830070404</identifier><identifier>PMID: 546221</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Ammonia - blood ; AMP Deaminase - analysis ; Anemia, Sickle Cell - blood ; Anemia, Sickle Cell - drug therapy ; Blood Urea Nitrogen ; Female ; Humans ; hyperammonemia ; Liver Diseases - etiology ; Male ; sickle cell anemia ; zinc ; Zinc - deficiency ; Zinc - pharmacology ; Zinc - therapeutic use</subject><ispartof>American journal of hematology, 1979-01, Vol.7 (4), p.323-327</ispartof><rights>Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3394-236f71dcc9484a41e91c7c6b87572020cb4f8d6dc170b3b5d03e94d917237cc73</citedby><cites>FETCH-LOGICAL-c3394-236f71dcc9484a41e91c7c6b87572020cb4f8d6dc170b3b5d03e94d917237cc73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.2830070404$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.2830070404$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/546221$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Prasad, Ananda S.</creatorcontrib><creatorcontrib>Rabbani, Parviz</creatorcontrib><creatorcontrib>Warth, James A.</creatorcontrib><title>Effect of zinc on hyperammonemia in sickle cell anemia subjects</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>An increase in plasma ammonia level in human volunteers on restricted zinc intake, and in zinc‐deficient rats, has recently been reported. Inasmuch as zinc deficiency has been observed in sickle cell anemia patients, we measured plasma ammonia levels in such subjects. In this report we document hyperammonemia in sickle cell anemia patients that was corrected with zinc therapy.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Ammonia - blood</subject><subject>AMP Deaminase - analysis</subject><subject>Anemia, Sickle Cell - blood</subject><subject>Anemia, Sickle Cell - drug therapy</subject><subject>Blood Urea Nitrogen</subject><subject>Female</subject><subject>Humans</subject><subject>hyperammonemia</subject><subject>Liver Diseases - etiology</subject><subject>Male</subject><subject>sickle cell anemia</subject><subject>zinc</subject><subject>Zinc - deficiency</subject><subject>Zinc - pharmacology</subject><subject>Zinc - therapeutic use</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAUhS3EqxRWJgZPbCnXj8TxhKqqUFAlFpgtx7FVlzxK3AiVX4-rVMDGdK_uOffT0UHomsCEANA7vV5NaM4ABHDgR2hEQGZJnqX0GI2AZSTuIM_RRQhrAEJ4DmfoNOUZpWSE7ufOWbPFrcNfvjG4bfBqt7Gdruu2sbXX2Dc4ePNeWWxsVWE9XENfrONfuEQnTlfBXh3mGL09zF9ni2T58vg0my4Tw5jkCWWZE6Q0RvKca06sJEaYrMhFKihQMAV3eZmVhggoWJGWwKzkpSSCMmGMYGN0O3A3XfvR27BVtQ_7QDFP2wcluGRCCB6Nk8FoujaEzjq16Xytu50ioPaFqViY-i0sPtwcyH1R2_LHPjQUZTnIn76yu39gavq8-IP-BiHZdXM</recordid><startdate>19790101</startdate><enddate>19790101</enddate><creator>Prasad, Ananda S.</creator><creator>Rabbani, Parviz</creator><creator>Warth, James A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19790101</creationdate><title>Effect of zinc on hyperammonemia in sickle cell anemia subjects</title><author>Prasad, Ananda S. ; Rabbani, Parviz ; Warth, James A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3394-236f71dcc9484a41e91c7c6b87572020cb4f8d6dc170b3b5d03e94d917237cc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Ammonia - blood</topic><topic>AMP Deaminase - analysis</topic><topic>Anemia, Sickle Cell - blood</topic><topic>Anemia, Sickle Cell - drug therapy</topic><topic>Blood Urea Nitrogen</topic><topic>Female</topic><topic>Humans</topic><topic>hyperammonemia</topic><topic>Liver Diseases - etiology</topic><topic>Male</topic><topic>sickle cell anemia</topic><topic>zinc</topic><topic>Zinc - deficiency</topic><topic>Zinc - pharmacology</topic><topic>Zinc - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Prasad, Ananda S.</creatorcontrib><creatorcontrib>Rabbani, Parviz</creatorcontrib><creatorcontrib>Warth, James A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Prasad, Ananda S.</au><au>Rabbani, Parviz</au><au>Warth, James A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of zinc on hyperammonemia in sickle cell anemia subjects</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>1979-01-01</date><risdate>1979</risdate><volume>7</volume><issue>4</issue><spage>323</spage><epage>327</epage><pages>323-327</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><abstract>An increase in plasma ammonia level in human volunteers on restricted zinc intake, and in zinc‐deficient rats, has recently been reported. Inasmuch as zinc deficiency has been observed in sickle cell anemia patients, we measured plasma ammonia levels in such subjects. In this report we document hyperammonemia in sickle cell anemia patients that was corrected with zinc therapy.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>546221</pmid><doi>10.1002/ajh.2830070404</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Adult Ammonia - blood AMP Deaminase - analysis Anemia, Sickle Cell - blood Anemia, Sickle Cell - drug therapy Blood Urea Nitrogen Female Humans hyperammonemia Liver Diseases - etiology Male sickle cell anemia zinc Zinc - deficiency Zinc - pharmacology Zinc - therapeutic use |
title | Effect of zinc on hyperammonemia in sickle cell anemia subjects |
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