Quinacrine Fluorescence Patterns of Human D Group Chromosomes

Quinacrine Fluorescence Patterns of Human D Group Chromosomes

Quinacrine fluorescence patterns have been used to identify ten different numerical and structural abnormalities of human chromosomes 13, 14 and 15. There are several advantages of this method over autoradiographic and morphological methods.

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Bibliographische Detailangaben
Veröffentlicht in:Nature (London) 1971-07, Vol.232 (5305), p.24-27
Hauptverfasser: MILLER, D. A, ALLDERDICE, P. W, MILLER, O. J, BREG, W. R
Format: Artikel
Sprache:eng
Schlagworte:
Autoradiography
Chromosome Aberrations - diagnosis
Chromosome Disorders
Chromosomes, Human, 13-15
Down Syndrome - diagnosis
Fluorescence
Humanities and Social Sciences
Humans
Karyotyping
Methods
multidisciplinary
Quinacrine
Science
Science (multidisciplinary)
Trisomy
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Beschreibung
Zusammenfassung:Quinacrine fluorescence patterns have been used to identify ten different numerical and structural abnormalities of human chromosomes 13, 14 and 15. There are several advantages of this method over autoradiographic and morphological methods.
ISSN:0028-0836
1476-4687
DOI:10.1038/232024a0