The epidemiology of Wilson's disease in the German Democratic Republic and current problems from the viewpoint of population genetics
Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, su...
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| Veröffentlicht in: | Psychiatrie, Neurologie, und medizinische Psychologie Neurologie, und medizinische Psychologie, 1979-07, Vol.31 (7), p.393-400 |
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| container_title | Psychiatrie, Neurologie, und medizinische Psychologie |
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| creator | Bachmann, H Lössner, J Gruss, B Ruchholtz, U |
| description | Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling. |
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Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling.</description><identifier>ISSN: 0033-2739</identifier><identifier>PMID: 542546</identifier><language>ger</language><publisher>Germany</publisher><subject>Genetics, Population ; Germany, East ; Hepatolenticular Degeneration - epidemiology ; Hepatolenticular Degeneration - genetics ; Humans</subject><ispartof>Psychiatrie, Neurologie, und medizinische Psychologie, 1979-07, Vol.31 (7), p.393-400</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/542546$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bachmann, H</creatorcontrib><creatorcontrib>Lössner, J</creatorcontrib><creatorcontrib>Gruss, B</creatorcontrib><creatorcontrib>Ruchholtz, U</creatorcontrib><title>The epidemiology of Wilson's disease in the German Democratic Republic and current problems from the viewpoint of population genetics</title><title>Psychiatrie, Neurologie, und medizinische Psychologie</title><addtitle>Psychiatr Neurol Med Psychol (Leipz)</addtitle><description>Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. 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Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling.</abstract><cop>Germany</cop><pmid>542546</pmid><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0033-2739 |
| ispartof | Psychiatrie, Neurologie, und medizinische Psychologie, 1979-07, Vol.31 (7), p.393-400 |
| issn | 0033-2739 |
| language | ger |
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| source | Jstor Complete Legacy; MEDLINE |
| subjects | Genetics, Population Germany, East Hepatolenticular Degeneration - epidemiology Hepatolenticular Degeneration - genetics Humans |
| title | The epidemiology of Wilson's disease in the German Democratic Republic and current problems from the viewpoint of population genetics |
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