An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern

An epidemic of meningococcal infection at Zaria, Northern Nigeria. 2. The changing clinical pattern

1,003 patients with meningococcal disease admitted to a single hospital during the course of a three-month epidemic were studied. A progressive decline in mortality, especially among patients with acute meningococcaemia, and a falling incidence of systemic and severe neurological complications among...

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Veröffentlicht in:Transactions of the Royal Society of Tropical Medicine and Hygiene 1979, Vol.73 (5), p.563-566
Hauptverfasser: Greenwood, B.M., Cleland, P.G., Haggie, M.H.K., Lewis, L.S., Macfarlane, J.T., Taqi, A., Whittle, H.C.
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Adolescent
Adult
Child
Child, Preschool
Disease Outbreaks - epidemiology
Female
Humans
Infant
Infant, Newborn
Male
Meningitis, Meningococcal - complications
Meningitis, Meningococcal - epidemiology
Meningitis, Meningococcal - mortality
Meningococcal Infections - complications
Meningococcal Infections - drug therapy
Meningococcal Infections - epidemiology
Nigeria
Sepsis - etiology
Sepsis - mortality
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Zusammenfassung:1,003 patients with meningococcal disease admitted to a single hospital during the course of a three-month epidemic were studied. A progressive decline in mortality, especially among patients with acute meningococcaemia, and a falling incidence of systemic and severe neurological complications among patients with meningitis were observed. It is suggested that the virulence of the causative group A meningococcus declined as the epidemic progressed.
ISSN:0035-9203
1878-3503
DOI:10.1016/0035-9203(79)90053-1