Phagocytosis and Intracellular Fate of Sporothrix schenckii
Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H2O2, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest t...
Gespeichert in:
| Veröffentlicht in: | The Journal of infectious diseases 1979-12, Vol.140 (5), p.815-817 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 817 |
|---|---|
| container_issue | 5 |
| container_start_page | 815 |
| container_title | The Journal of infectious diseases |
| container_volume | 140 |
| creator | Cunningham, K. M. Bulmer, G. S. Rhoades, E. R. |
| description | Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H2O2, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest that PMNLs may play an important role in host resistance to infection with S. schenckii. |
| doi_str_mv | 10.1093/infdis/140.5.815 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_74914950</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>30081666</jstor_id><sourcerecordid>30081666</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-48f66fcf70fc1fe4f69699cb634e40630ddfb3c455f90d2f80adf5182ab651543</originalsourceid><addsrcrecordid>eNo9kEtLAzEURoP4qtW9C4VZuZv2ZvKYCa6kWFsoqFRB3IQ0k9j0ManJFNp_75SRru7i3O-7l4PQLYYeBkH6rrKli31Mocd6BWYnqIMZyVPOMTlFHYAsS3EhxCW6inEBAJTw_AKdZwRDTjro8W2ufrze1z66mKiqTMZVHZQ2q9V2pUIyVLVJvE2mGx98PQ9ul0Q9N5VeOneNzqxaRXPzP7voc_j8MRilk9eX8eBpkmqKRZ3SwnJutc3BamwNtVxwIfSME2oocAJlaWdEU8asgDKzBajSMlxkasYZZpR00UPbuwn-d2tiLdcuHj5UlfHbKHMqMBUMmkVoF3XwMQZj5Sa4tQp7iUEedMlWl2x0SSYbXU3k7r97O1ub8hho_TT4vsWLWPtwpASgwJzzhqctd7E2uyNXYSl5TnImR1_fzbXRNGNUyHfyB08Ef7g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74914950</pqid></control><display><type>article</type><title>Phagocytosis and Intracellular Fate of Sporothrix schenckii</title><source>MEDLINE</source><source>JSTOR</source><creator>Cunningham, K. M. ; Bulmer, G. S. ; Rhoades, E. R.</creator><creatorcontrib>Cunningham, K. M. ; Bulmer, G. S. ; Rhoades, E. R.</creatorcontrib><description>Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H2O2, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest that PMNLs may play an important role in host resistance to infection with S. schenckii.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/140.5.815</identifier><identifier>PMID: 231073</identifier><language>eng</language><publisher>United States: The University of Chicago Press</publisher><subject>Candida albicans - immunology ; Cell Survival ; Chemical suspensions ; Chlorides - pharmacology ; Cryptococcus neoformans ; Fungi ; Half-Life ; Hospital administration ; Humans ; Iodides - pharmacology ; Leukocytes ; Neutrophils ; Neutrophils - microbiology ; Peroxidase - pharmacology ; Phagocytosis ; Sporothrix ; Sporothrix - immunology ; Sporotrichosis ; Yeasts</subject><ispartof>The Journal of infectious diseases, 1979-12, Vol.140 (5), p.815-817</ispartof><rights>Copyright 1979 The University of Chicago</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-48f66fcf70fc1fe4f69699cb634e40630ddfb3c455f90d2f80adf5182ab651543</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/30081666$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/30081666$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/231073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cunningham, K. M.</creatorcontrib><creatorcontrib>Bulmer, G. S.</creatorcontrib><creatorcontrib>Rhoades, E. R.</creatorcontrib><title>Phagocytosis and Intracellular Fate of Sporothrix schenckii</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H2O2, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest that PMNLs may play an important role in host resistance to infection with S. schenckii.</description><subject>Candida albicans - immunology</subject><subject>Cell Survival</subject><subject>Chemical suspensions</subject><subject>Chlorides - pharmacology</subject><subject>Cryptococcus neoformans</subject><subject>Fungi</subject><subject>Half-Life</subject><subject>Hospital administration</subject><subject>Humans</subject><subject>Iodides - pharmacology</subject><subject>Leukocytes</subject><subject>Neutrophils</subject><subject>Neutrophils - microbiology</subject><subject>Peroxidase - pharmacology</subject><subject>Phagocytosis</subject><subject>Sporothrix</subject><subject>Sporothrix - immunology</subject><subject>Sporotrichosis</subject><subject>Yeasts</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEURoP4qtW9C4VZuZv2ZvKYCa6kWFsoqFRB3IQ0k9j0ManJFNp_75SRru7i3O-7l4PQLYYeBkH6rrKli31Mocd6BWYnqIMZyVPOMTlFHYAsS3EhxCW6inEBAJTw_AKdZwRDTjro8W2ufrze1z66mKiqTMZVHZQ2q9V2pUIyVLVJvE2mGx98PQ9ul0Q9N5VeOneNzqxaRXPzP7voc_j8MRilk9eX8eBpkmqKRZ3SwnJutc3BamwNtVxwIfSME2oocAJlaWdEU8asgDKzBajSMlxkasYZZpR00UPbuwn-d2tiLdcuHj5UlfHbKHMqMBUMmkVoF3XwMQZj5Sa4tQp7iUEedMlWl2x0SSYbXU3k7r97O1ub8hho_TT4vsWLWPtwpASgwJzzhqctd7E2uyNXYSl5TnImR1_fzbXRNGNUyHfyB08Ef7g</recordid><startdate>19791201</startdate><enddate>19791201</enddate><creator>Cunningham, K. M.</creator><creator>Bulmer, G. S.</creator><creator>Rhoades, E. R.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19791201</creationdate><title>Phagocytosis and Intracellular Fate of Sporothrix schenckii</title><author>Cunningham, K. M. ; Bulmer, G. S. ; Rhoades, E. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-48f66fcf70fc1fe4f69699cb634e40630ddfb3c455f90d2f80adf5182ab651543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Candida albicans - immunology</topic><topic>Cell Survival</topic><topic>Chemical suspensions</topic><topic>Chlorides - pharmacology</topic><topic>Cryptococcus neoformans</topic><topic>Fungi</topic><topic>Half-Life</topic><topic>Hospital administration</topic><topic>Humans</topic><topic>Iodides - pharmacology</topic><topic>Leukocytes</topic><topic>Neutrophils</topic><topic>Neutrophils - microbiology</topic><topic>Peroxidase - pharmacology</topic><topic>Phagocytosis</topic><topic>Sporothrix</topic><topic>Sporothrix - immunology</topic><topic>Sporotrichosis</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cunningham, K. M.</creatorcontrib><creatorcontrib>Bulmer, G. S.</creatorcontrib><creatorcontrib>Rhoades, E. R.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cunningham, K. M.</au><au>Bulmer, G. S.</au><au>Rhoades, E. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phagocytosis and Intracellular Fate of Sporothrix schenckii</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>1979-12-01</date><risdate>1979</risdate><volume>140</volume><issue>5</issue><spage>815</spage><epage>817</epage><pages>815-817</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><abstract>Human polymorphonuclear leukocytes (PMNLs) phagocytized and killed yeast-phase cells of Sporothrix schenckii in vitro in the presence of 10% unheated serum. The combination of H2O2, KI, and human PMNL myeloperoxidase was lethal to yeast-phase S. schenckii. The results of this investigation suggest that PMNLs may play an important role in host resistance to infection with S. schenckii.</abstract><cop>United States</cop><pub>The University of Chicago Press</pub><pmid>231073</pmid><doi>10.1093/infdis/140.5.815</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 1979-12, Vol.140 (5), p.815-817 |
| issn | 0022-1899 1537-6613 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74914950 |
| source | MEDLINE; JSTOR |
| subjects | Candida albicans - immunology Cell Survival Chemical suspensions Chlorides - pharmacology Cryptococcus neoformans Fungi Half-Life Hospital administration Humans Iodides - pharmacology Leukocytes Neutrophils Neutrophils - microbiology Peroxidase - pharmacology Phagocytosis Sporothrix Sporothrix - immunology Sporotrichosis Yeasts |
| title | Phagocytosis and Intracellular Fate of Sporothrix schenckii |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T13%3A39%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Phagocytosis%20and%20Intracellular%20Fate%20of%20Sporothrix%20schenckii&rft.jtitle=The%20Journal%20of%20infectious%20diseases&rft.au=Cunningham,%20K.%20M.&rft.date=1979-12-01&rft.volume=140&rft.issue=5&rft.spage=815&rft.epage=817&rft.pages=815-817&rft.issn=0022-1899&rft.eissn=1537-6613&rft_id=info:doi/10.1093/infdis/140.5.815&rft_dat=%3Cjstor_proqu%3E30081666%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74914950&rft_id=info:pmid/231073&rft_jstor_id=30081666&rfr_iscdi=true |