RIFLE Criteria for Cardiac Surgery–Associated Acute Kidney Injury: Risk Factors and Outcomes

The aims of this study were to identify risk factors and evaluate the association with clinical outcomes of postoperative cardiac surgery–associated acute kidney injury (CSA‐AKI). Data from 2488 consecutive adult patients were analyzed. Patients were classified as having CSA‐AKI based on the risk, injury, failure, loss of kidney function, and end‐stage kidney disease (RIFLE) criteria using peak postoperative creatinine in the postoperative intensive care unit (ICU). Multiple stepwise logistic regression analysis was used to identify independent risk factors for CSA‐AKI. CSA‐AKI occurred in 584 patients (23.5%). CSA‐AKI patients had significantly longer aortic cross‐clamp and cardiopulmonary bypass times. Furthermore, CSA‐AKI patients had higher hospital mortality (5.5% vs 1.5%, P